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"How to Save a Life" is a hit song by the American rock band The Fray, released in 2006 as part of their debut album of the same name. Written by lead vocalist Isaac Slade and keyboardist Joe King, the song addresses themes of communication and the challenges of helping someone in crisis. It gained widespread acclaim for its emotional depth and relatable lyrics, resonating with listeners worldwide. The track achieved significant chart success, reaching the top of the Billboard Adult Pop Songs chart, and received a Grammy nomination for Best Pop Performance by a Duo or Group with Vocals. Additionally, "How to Save a Life" was prominently featured in the television series "Grey's Anatomy," further boosting its popularity and cultural impact.